{"id":1750,"date":"2012-11-14T20:03:50","date_gmt":"2012-11-14T20:03:50","guid":{"rendered":"https:\/\/ecm.eng.auburn.edu\/wp\/emag\/?p=1750"},"modified":"2012-11-27T17:31:30","modified_gmt":"2012-11-27T17:31:30","slug":"into-the-lab-chemical-3","status":"publish","type":"post","link":"https:\/\/ecm.eng.auburn.edu\/wp\/emag\/?p=1750","title":{"rendered":"Into the Lab: Chemical"},"content":{"rendered":"

Allan David, John W. Brown assistant professor in chemical engineering, is conducting research in \u201csmart nanomaterials,\u201d nanoparticles and nanocomposites that respond to changes in their environment. While David will explore a wide array of applications for \u201csmart nanomaterials,\u201d his primary focus will be biomedicine. One project, for example, will utilize multimodal imaging agents to improve cancer diagnostics.<\/p>\n

Using nanoparticles with a controlled shape, size and composition, David is developing injectable materials that seek out cancer cells, recognize the presence of biologically active markers and identify the cancer\u2019s rate of growth. By using diagnostic tools such as magnetic resonance imaging and positron emission tomography, or a PET scan, practitioners can observe the nanoparticles and study signal responses to analyze the aggressiveness of various cancers, such as brain and prostate cancer, as well as how to effectively treat them.<\/p>\n

\u201cIn some cases, such as with brain tumors or prostate cancer, patients are told to \u2018wait and see\u2019 because no effective therapies are available and the risk of side-effects is greater than the benefits of therapy,\u201d says David. \u201cIf we could non-invasively measure whether the cancer is aggressive or indolent, a more effective and personalized therapeutic regimen can be designed for each patient.\u201d<\/p>\n

While nanoparticles are not new, David\u2019s research explores making an impact in their application. His project will focus on developing nanoparticles and targeting them to specific cancers, making them sensitive to tumor-specific processes, and then evaluating their safety and efficacy.<\/p>\n

\u201cWe have these materials, but they\u2019re not really in a form that\u2019s easily translated to the clinic,\u201d says David.<\/p>\n

He will be collaborating with faculty members Robert Arnold and David Riese in Auburn\u2019s Harrison School of Pharmacy and Valery Petrenko in the College of Veterinary Medicine, as well as Engineering Dean Christopher Roberts and MRI Center Director Thomas Denney.<\/p>\n

<\/div>
\"Flickr\"<\/a> view  Auburn Engineering<\/a> on flickr   \"Auburn<\/a><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"

Allan David, John W. Brown assistant professor in chemical engineering, is conducting research in \u201csmart nanomaterials,\u201d nanoparticles and nanocomposites that respond to changes in their environment. While David will explore a wide array of applications for \u201csmart nanomaterials,\u201d his primary focus will be biomedicine. One project, for example, will utilize […]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[7],"tags":[181,179,177,43,52,178,180,117,27],"yoast_head":"\nInto the Lab: Chemical » Auburn Engineer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ecm.eng.auburn.edu\/wp\/emag\/?p=1750\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Into the Lab: Chemical » Auburn Engineer\" \/>\n<meta property=\"og:description\" content=\"Allan David, John W. Brown assistant professor in chemical engineering, is conducting research in \u201csmart nanomaterials,\u201d nanoparticles and nanocomposites that respond to changes in their environment. 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